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Heat Shock Protein 90 Inhibition in Lung Cancer
The heat shock protein 90 (Hsp90) chaperone is required for the conformational maturation and stability of multiple oncogenic kinases that drive signal transduction and proliferation of lung cancer cells. The recent demonstration that mutant epidermal growth factor receptor is an Hsp90 client, irres...
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| Pubblicato in: | J Thorac Oncol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475350/ https://ncbi.nlm.nih.gov/pubmed/18520302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318174ea3a |
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