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Heat Shock Protein 90 Inhibition in Lung Cancer

The heat shock protein 90 (Hsp90) chaperone is required for the conformational maturation and stability of multiple oncogenic kinases that drive signal transduction and proliferation of lung cancer cells. The recent demonstration that mutant epidermal growth factor receptor is an Hsp90 client, irres...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Thorac Oncol
Prif Awduron: Shimamura, Takeshi, Shapiro, Geoffrey I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475350/
https://ncbi.nlm.nih.gov/pubmed/18520302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318174ea3a
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