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Heat Shock Protein 90 Inhibition in Lung Cancer
The heat shock protein 90 (Hsp90) chaperone is required for the conformational maturation and stability of multiple oncogenic kinases that drive signal transduction and proliferation of lung cancer cells. The recent demonstration that mutant epidermal growth factor receptor is an Hsp90 client, irres...
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| Publié dans: | J Thorac Oncol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475350/ https://ncbi.nlm.nih.gov/pubmed/18520302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318174ea3a |
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