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Heat Shock Protein 90 Inhibition in Lung Cancer

The heat shock protein 90 (Hsp90) chaperone is required for the conformational maturation and stability of multiple oncogenic kinases that drive signal transduction and proliferation of lung cancer cells. The recent demonstration that mutant epidermal growth factor receptor is an Hsp90 client, irres...

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Dades bibliogràfiques
Publicat a:J Thorac Oncol
Autors principals: Shimamura, Takeshi, Shapiro, Geoffrey I.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475350/
https://ncbi.nlm.nih.gov/pubmed/18520302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318174ea3a
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