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Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State
Envelope glycoprotein gp120 of HIV-1 possesses several variable regions whose precise structure has been difficult to establish. We report a new model of gp120, in complex with antibodies CD4 and 17b, complete with its variable regions. The model was produced by a computational protocol which uses c...
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| Yayımlandı: | Structure |
|---|---|
| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474864/ https://ncbi.nlm.nih.gov/pubmed/26039348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.03.026 |
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