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Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity

During the development of type 2 diabetes, endoplasmic reticulum (ER) stress leads to not only insulin resistance but also to pancreatic beta cell failure. Conversely, cell function under various stressed conditions can be restored by reducing ER stress by activating AMP-activated protein kinase (AM...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Matsuda, Tomokazu, Takahashi, Hiroaki, Mieda, Yusuke, Shimizu, Shinobu, Kawamoto, Takeshi, Matsuura, Yuki, Takai, Tomoko, Suzuki, Emi, Kanno, Ayumi, Koyanagi-Kimura, Maki, Asahara, Shun-ichiro, Bartolome, Alberto, Yokoi, Norihide, Inoue, Hiroshi, Ogawa, Wataru, Seino, Susumu, Kido, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474801/
https://ncbi.nlm.nih.gov/pubmed/26091000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130757
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