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Response of Head and Neck Squamous Cell Carcinoma Cells Carrying PIK3CA Mutations to Select Targeted Therapies

IMPORTANCE: The PIK3CA mutation is one of the most common mutations in Head and Neck Squamous Cell Carcinoma (HNSCC). Through this research we attempt to elicit the role of oncogene dependence and effects of targeted therapy on this PIK3CA mutation. OBJECTIVES: 1) To determine the role of oncogene d...

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Bibliografiske detaljer
Udgivet i:JAMA Otolaryngol Head Neck Surg
Main Authors: Wirtz, Eric D, Hoshino, Daisuke, Maldonado, Anthony T, Tyson, Darren R, Weaver, Alissa M
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474763/
https://ncbi.nlm.nih.gov/pubmed/25855885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoto.2015.0471
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