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Contrasting Effects of Two Lipid Cofactors of Prion Replication on the Conformation of the Prion Protein
Recent studies introduced two experimental protocols for converting full-length recombinant prion protein (rPrP) purified from E.coli into the infectious prion state (PrP(Sc)) with high infectivity titers. Both protocols employed protein misfolding cyclic amplification (PMCA) for generating PrP(Sc)...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474664/ https://ncbi.nlm.nih.gov/pubmed/26090881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130283 |
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