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Analysis of covalent modifications of amyloidogenic proteins using two-dimensional electrophoresis: prion protein and its sialylation
A number of proteins associated with neurodegenerative disease undergo several types of post-translational modifications. They include N-linked glycosylation of the prion protein and amyloid precursor protein, phosphorylation of tau and α-synuclein. Post-translational modifications alter physical pr...
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| Опубликовано в: : | Methods Mol Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7052952/ https://ncbi.nlm.nih.gov/pubmed/29886537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7816-8_15 |
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