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Neuronal Subtype and Satellite Cell Tropism Are Determinants of Varicella-Zoster Virus Virulence in Human Dorsal Root Ganglia Xenografts In Vivo

Varicella zoster virus (VZV), a human alphaherpesvirus, causes varicella during primary infection. VZV reactivation from neuronal latency may cause herpes zoster, post herpetic neuralgia (PHN) and other neurologic syndromes. To investigate VZV neuropathogenesis, we developed a model using human dors...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Zerboni, Leigh, Arvin, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474629/
https://ncbi.nlm.nih.gov/pubmed/26090802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004989
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