Conditional U1 Gene Silencing in Toxoplasma gondii

The functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencing. U1 snRNP is critical in pre-mRNA splicing by defini...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Pieperhoff, Manuela S., Pall, Gurman S., Jiménez-Ruiz, Elena, Das, Sujaan, Melatti, Carmen, Gow, Matthew, Wong, Eleanor H., Heng, Joanne, Müller, Sylke, Blackman, Michael J., Meissner, Markus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474610/
https://ncbi.nlm.nih.gov/pubmed/26090798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130356
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