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Overexpression of the Large-Conductance, Ca(2+)-Activated K(+) (BK) Channel Shortens Action Potential Duration in HL-1 Cardiomyocytes

Long QT syndrome is characterized by a prolongation of the interval between the Q wave and the T wave on the electrocardiogram. This abnormality reflects a prolongation of the ventricular action potential caused by a number of genetic mutations or a variety of drugs. Since effective treatments are u...

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Udgivet i:PLoS One
Main Authors: Stimers, Joseph R., Song, Li, Rusch, Nancy J., Rhee, Sung W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474436/
https://ncbi.nlm.nih.gov/pubmed/26091273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130588
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