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Pathway-Dependent Effectiveness of Network Algorithms for Gene Prioritization

A network-based approach has proven useful for the identification of novel genes associated with complex phenotypes, including human diseases. Because network-based gene prioritization algorithms are based on propagating information of known phenotype-associated genes through networks, the pathway s...

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Publicat a:PLoS One
Autors principals: Shim, Jung Eun, Hwang, Sohyun, Lee, Insuk
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474432/
https://ncbi.nlm.nih.gov/pubmed/26091506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130589
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