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Prioritizing candidate disease genes by network-based boosting of genome-wide association data
Network “guilt by association” (GBA) is a proven approach for identifying novel disease genes based on the observation that similar mutational phenotypes arise from functionally related genes. In principle, this approach could account even for nonadditive genetic interactions, which underlie the syn...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129253/ https://ncbi.nlm.nih.gov/pubmed/21536720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.118992.110 |
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