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Prioritizing candidate disease genes by network-based boosting of genome-wide association data

Network “guilt by association” (GBA) is a proven approach for identifying novel disease genes based on the observation that similar mutational phenotypes arise from functionally related genes. In principle, this approach could account even for nonadditive genetic interactions, which underlie the syn...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lee, Insuk, Blom, U. Martin, Wang, Peggy I., Shim, Jung Eun, Marcotte, Edward M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129253/
https://ncbi.nlm.nih.gov/pubmed/21536720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.118992.110
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