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Adaptive Mutations That Occurred during Circulation in Humans of H1N1 Influenza Virus in the 2009 Pandemic Enhance Virulence in Mice

During the 2009 H1N1 influenza pandemic, infection attack rates were particularly high among young individuals who suffered from pneumonia with occasional death. Moreover, previously reported determinants of mammalian adaptation and pathogenicity were not present in 2009 pandemic H1N1 influenza A vi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Otte, A., Sauter, M., Daxer, M. A., McHardy, A. C., Klingel, K., Gabriel, G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473582/
https://ncbi.nlm.nih.gov/pubmed/25948752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00665-15
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