Naturally Occurring Human Monoclonal Antibodies Neutralize both 1918 and 2009 Pandemic Influenza A (H1N1) Viruses

The 2009 pandemic influenza A (H1N1) virus exhibits hemagglutinin protein sequence homology with the 1918 pandemic influenza virus. We found that human monoclonal antibodies recognized the Sa antigenic site on the head domains of both 1918 and 2009 hemagglutinins, a site that is hypervariable due to...

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Detalhes bibliográficos
Main Authors: Krause, Jens C., Tumpey, Terrence M., Huffman, Chelsey J., McGraw, Patricia A., Pearce, Melissa B., Tsibane, Tshidi, Hai, Rong, Basler, Christopher F., Crowe, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826039/
https://ncbi.nlm.nih.gov/pubmed/20042511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02184-09
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