Rift Valley Fever Virus MP-12 Vaccine Is Fully Attenuated by a Combination of Partial Attenuations in the S, M, and L Segments

Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and characterized by a high rate of abortion in ruminants and hemorrhagic fever, encephalitis, or blindness in humans. RVF is caused by Rift Valley fever virus (RVFV; family Bunyaviridae, genus Phlebovirus), which has a t...

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Vydáno v:J Virol
Hlavní autoři: Ikegami, Tetsuro, Hill, Terence E., Smith, Jennifer K., Zhang, Lihong, Juelich, Terry L., Gong, Bin, Slack, Olga A. L., Ly, Hoai J., Lokugamage, Nandadeva, Freiberg, Alexander N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473576/
https://ncbi.nlm.nih.gov/pubmed/25948740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00135-15
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