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Genetic Subpopulations of Rift Valley Fever Virus Strains ZH548 and MP-12 and Recombinant MP-12 Strains

Rift Valley fever virus strain MP-12 was generated by serial plaque passages of parental strain ZH548 12 times in MRC-5 cells in the presence of a chemical mutagen, 5-fluorouracil. As a result, MP-12 encoded 4, 9, and 10 mutations in the S, M, and L segments, respectively. Among them, mutations in t...

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Autors principals: Lokugamage, Nandadeva, Freiberg, Alexander N., Morrill, John C., Ikegami, Tetsuro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503115/
https://ncbi.nlm.nih.gov/pubmed/23035230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02081-12
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