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Immediate and Ongoing Detection of Prions in the Blood of Hamsters and Deer following Oral, Nasal, or Blood Inoculations

Infectious prions traverse epithelial barriers to gain access to the circulatory system, yet the temporal parameters of transepithelial transport and persistence in the blood over time remain unknown. We used whole-blood real-time quaking-induced conversion (wbRT-QuIC) to analyze whole blood collect...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Elder, Alan M., Henderson, Davin M., Nalls, Amy V., Hoover, Edward A., Kincaid, Anthony E., Bartz, Jason C., Mathiason, Candace K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473550/
https://ncbi.nlm.nih.gov/pubmed/25926635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00760-15
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