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NF-κB inhibitor reverses temozolomide resistance in human glioma TR/U251 cells

Glioblastoma multiforme (GBM) demonstrates an unsatisfactory clinical prognosis due to the intrinsic or acquired resistance to temozolomide (TMZ) exhibited by the tumors. One possible cause of TMZ resistance in GBM is the overexpression of O(6)-methylguanine-DNA methyltransferase (MGMT), which can r...

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Bibliografski detalji
Izdano u:Oncol Lett
Glavni autori: WANG, XUAN, JIA, LILI, JIN, XIAOHUA, LIU, QIAN, CAO, WEI, GAO, XIANGDONG, YANG, MINGFENG, SUN, BAOLIANG
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473369/
https://ncbi.nlm.nih.gov/pubmed/26137111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3130
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