Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway

Hepatic progenitor cells (HPCs) appear to play an important role in chronic liver injury. In this study, cirrhosis was induced in F-344 rats (n = 32) via subcutaneous injection of 50% carbon tetrachloride (CCl(4)) twice a week for 8 weeks. Then, 30% CCl(4) was administered in conjunction with intrag...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chen, Jiamei, Zhang, Xiao, Xu, Ying, Li, Xuewei, Ren, Shuang, Zhou, Yaning, Duan, Yuyou, Zern, Mark, Zhang, Hua, Chen, Gaofeng, Liu, Chenghai, Mu, Yongping, Liu, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473299/
https://ncbi.nlm.nih.gov/pubmed/26087010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130310
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