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CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

Although cytomegalovirus (CMV) reactivation has long been implicated in posttransplant immune dysfunction, the molecular mechanisms that drive this phenomenon remain undetermined. To address this, we combined multiparameter flow cytometric analysis and T-cell subpopulation sorting with high-throughp...

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Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Suessmuth, Yvonne, Mukherjee, Rithun, Watkins, Benjamin, Koura, Divya T., Finstermeier, Knut, Desmarais, Cindy, Stempora, Linda, Horan, John T., Langston, Amelia, Qayed, Muna, Khoury, Hanna J., Grizzle, Audrey, Cheeseman, Jennifer A., Conger, Jason A., Robertson, Jennifer, Garrett, Aneesah, Kirk, Allan D., Waller, Edmund K., Blazar, Bruce R., Mehta, Aneesh K., Robins, Harlan S., Kean, Leslie S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473113/
https://ncbi.nlm.nih.gov/pubmed/25852054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-631853
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