CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

Although cytomegalovirus (CMV) reactivation has long been implicated in posttransplant immune dysfunction, the molecular mechanisms that drive this phenomenon remain undetermined. To address this, we combined multiparameter flow cytometric analysis and T-cell subpopulation sorting with high-throughp...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Suessmuth, Yvonne, Mukherjee, Rithun, Watkins, Benjamin, Koura, Divya T., Finstermeier, Knut, Desmarais, Cindy, Stempora, Linda, Horan, John T., Langston, Amelia, Qayed, Muna, Khoury, Hanna J., Grizzle, Audrey, Cheeseman, Jennifer A., Conger, Jason A., Robertson, Jennifer, Garrett, Aneesah, Kirk, Allan D., Waller, Edmund K., Blazar, Bruce R., Mehta, Aneesh K., Robins, Harlan S., Kean, Leslie S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Plenary Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473113/
https://ncbi.nlm.nih.gov/pubmed/25852054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-631853
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