Direct observation of substance P-induced internalization of neurokinin 1 (NK1) receptors at sites of inflammation.

Substance P (SP) can cause plasma leakage at sites of inflammation by binding to neurokinin type 1 (NK1) receptors on the surface of endothelial cells. Internalization after ligand binding could reduce the number of NK1 receptors on the cell surface and thus participate in the desensitization and re...

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Autors principals: Bowden, J J, Garland, A M, Baluk, P, Lefevre, P, Grady, E F, Vigna, S R, Bunnett, N W, McDonald, D M
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC44727/
https://ncbi.nlm.nih.gov/pubmed/7522326
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