Constitutive activation of Mek1 by mutation of serine phosphorylation sites.
A variety of extracellular signals lead to the phosphorylation and activation of mitogen-activated protein kinases (MAP kinases). An activator of MAP kinases, Mek1, phosphorylates MAP kinases at threonine and tyrosine residues and is itself phosphorylated at serine-218 and -222 by the protooncogene...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44726/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8090753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.8960 |
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