Surgical molecular navigation with a Ratiometric Activatable Cell Penetrating Peptide improves intraoperative identification and resection of small salivary gland cancers

BACKGROUND: We evaluated the use of intraoperative fluorescence guidance by enzymatically cleavable ratiometric activatable cell-penetrating peptide (RACPP(PLGC(Me)AG)) containing Cy5 as a fluorescent donor and Cy7 as a fluorescent acceptor for salivary gland cancer surgery in a mouse model. METHODS...

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Publicado en:Head Neck
Autores principales: Hussain, Timon, Savariar, Elamprakash N., Diaz-Perez, Julio A., Messer, Karen, Pu, Minya, Tsien, Roger Y., Nguyen, Quyen T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472578/
https://ncbi.nlm.nih.gov/pubmed/25521629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23946
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