c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas

Genomic amplification of the c-Jun proto-oncogene has been identified in ~30% of dedifferentiated liposarcomas (DDLPS), but the functional contribution of c-Jun to the progression of DDLPS remains poorly understood. In previous work, we showed that knockdown of c-Jun by RNA interference impaired the...

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Udgivet i:J Pathol
Main Authors: Sioletic, Stefano, Czaplinski, Jeffrey, Hu, Lan, Fletcher, Jonathan A., Fletcher, Christopher D.M., Wagner, Andrew J., Loda, Massimo, Demetri, George D., Sicinska, Ewa T., Snyder, Eric L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472460/
https://ncbi.nlm.nih.gov/pubmed/24852265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4379
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