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Fragment Screening of Infectious Disease Targets in a Structural Genomics Environment

Structural genomics efforts have traditionally focused on generating single protein structures of unique and diverse targets. However, a lone structure for a given target is often insufficient to firmly assign function or to drive drug discovery. As part of the Seattle Structural Genomics Center for...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Begley, Darren W, Davies, Douglas R, Hartley, Robert, Edwards, Thomas E, Staker, Bart L, Van Voorhis, Wesley C, Myler, Peter J, Stewart, Lance J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472360/
https://ncbi.nlm.nih.gov/pubmed/21371605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381274-2.00021-2
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