DNA Methylation-Guided Prediction of Clinical Failure in High-Risk Prostate Cancer

BACKGROUND: Prostate cancer (PCa) is a very heterogeneous disease with respect to clinical outcome. This study explored differential DNA methylation in a priori selected genes to diagnose PCa and predict clinical failure (CF) in high-risk patients. METHODS: A quantitative multiplex, methylation-spec...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Litovkin, Kirill, Van Eynde, Aleyde, Joniau, Steven, Lerut, Evelyne, Laenen, Annouschka, Gevaert, Thomas, Gevaert, Olivier, Spahn, Martin, Kneitz, Burkhard, Gramme, Pierre, Helleputte, Thibault, Isebaert, Sofie, Haustermans, Karin, Bollen, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472347/
https://ncbi.nlm.nih.gov/pubmed/26086362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130651
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