Monoclonal antibody-superantigen fusion proteins: tumor-specific agents for T-cell-based tumor therapy.

The bacterial superantigen staphylococcal enterotoxin A (SEA) is an extremely potent activator of T lymphocytes when presented on major histocompatibility complex (MHC) class II molecules. To develop a tumor-specific superantigen for cancer therapy, we have made a recombinant fusion protein of SEA a...

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Main Authors: Dohlsten, M, Abrahmsén, L, Björk, P, Lando, P A, Hedlund, G, Forsberg, G, Brodin, T, Gascoigne, N R, Förberg, C, Lind, P
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC44723/
https://ncbi.nlm.nih.gov/pubmed/8090750
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