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Therapy of human non-small-cell lung carcinoma using antibody targeting of a modified superantigen
Superantigens activate T-cells by linking the T-cell receptor to MHC class II on antigen-presenting cells, and novel reactivity can be introduced by fusing the superantigen to a targeting molecule. Thus, an antibody-targeted superantigen, which activates T cells to destroy tumour cells, might be use...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2001
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363924/ https://ncbi.nlm.nih.gov/pubmed/11437414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1891 |
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