Immunogens Modeling a Fusion-Intermediate Conformation of gp41 Elicit Antibodies to the Membrane Proximal External Region of the HIV Envelope Glycoprotein

The membrane proximal external region (MPER) of the gp41 subunit of the HIV-1 envelope glycoprotein (Env) contains determinants for broadly neutralizing antibodies and has remained an important focus of vaccine design. However, creating an immunogen that elicits broadly neutralizing antibodies to th...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Vassell, Russell, He, Yong, Vennakalanti, Prasad, Dey, Antu K., Zhuang, Min, Wang, Wei, Sun, Yide, Biron-Sorek, Zohar, Srivastava, Indresh K., LaBranche, Celia C., Montefiori, David C., Barnett, Susan W., Weiss, Carol D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472232/
https://ncbi.nlm.nih.gov/pubmed/26087072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128562
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