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Fast Decay of CaMKII FRET Sensor Signal in Spines after LTP Induction Is Not Due to Its Dephosphorylation

Because CaMKII is the critical Ca(2+) sensor that triggers long-term potentiation (LTP), understanding its activation and deactivation is important. A major advance has been the development of a FRET indicator of the conformational state of CaMKII called Camui. Experiments using Camui have demonstra...

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Udgivet i:PLoS One
Main Authors: Otmakhov, Nikolai, Regmi, Shaurav, Lisman, John E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472229/
https://ncbi.nlm.nih.gov/pubmed/26086939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130457
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