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The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

At the heart of the ribosome lie rRNAs, whose catalytic function in translation is subtly modulated by posttranscriptional modifications. In the small ribosomal subunit of budding yeast, on the 18S rRNA, two adjacent adenosines (A1781/A1782) are N(6)-dimethylated by Dim1 near the decoding site, and...

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Zorbas, Christiane, Nicolas, Emilien, Wacheul, Ludivine, Huvelle, Emmeline, Heurgué-Hamard, Valérie, Lafontaine, Denis L. J.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472018/
https://ncbi.nlm.nih.gov/pubmed/25851604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-02-0073
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