Facile Chemoenzymatic Synthesis of Biotinylated Heparosan Hexasaccharide

A biotinylated heparosan hexasaccharide was synthesized using one-pot multi-enzyme strategy, in situ activation and transfer of N-trifluoroacetylglucosamine (GlcNTFA) to heparin backbone significantly improved the synthetic efficiency. The biotinylated hexasaccharide could serve as a flexible core t...

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Foilsithe in:Org Biomol Chem
Main Authors: Wu, Baolin, Wei, Na, Thon, Vireak, Wei, Mohui, Yu, Zaikuan, Xu, Yongmei, Chen, Xi, Liu, Jian, Wang, Peng George, Li, Tiehai
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472006/
https://ncbi.nlm.nih.gov/pubmed/25858766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00462d
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