Association of Granulomatosis With Polyangiitis (Wegener’s) With HLA–DPB1*04 and SEMA6A Gene Variants Evidence From Genome-Wide Analysis

OBJECTIVE: To identify genetic determinants of granulomatosis with polyangiitis (Wegener’s) (GPA). METHODS: We carried out a genome-wide association study (GWAS) of 492 GPA cases and 1,506 healthy controls (white subjects of European descent), followed by replication analysis of the most strongly as...

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Pubblicato in:Arthritis Rheum
Autori principali: Xie, Gang, Roshandel, Delnaz, Sherva, Richard, Monach, Paul A., Lu, Emily Yue, Kung, Tabitha, Carrington, Keisha, Zhang, Steven S., Pulit, Sara L., Ripke, Stephan, Carette, Simon, Dellaripa, Paul F., Edberg, Jeffrey C., Hoffman, Gary S., Khalidi, Nader, Langford, Carol A., Mahr, Alfred D., St.Clair, E. William, Seo, Philip, Specks, Ulrich, Spiera, Robert F., Stone, John H., Ytterberg, Steven R., Raychaudhuri, Soumya, de Bakker, Paul I. W., Farrer, Lindsay A., Amos, Christopher I., Merkel, Peter A., Siminovitch, Katherine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471994/
https://ncbi.nlm.nih.gov/pubmed/23740775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38036
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