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WWOX: A fragile tumor suppressor
WWOX, the WW domain-containing oxidoreductase gene at chromosome region 16q23.3–q24.1, spanning chromosomal fragile site FRA16D, encodes the 46 kDa Wwox protein, a tumor suppressor that is lost or reduced in expression in a wide variety of cancers, including breast, prostate, ovarian, and lung. The...
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Pubblicato in: | Exp Biol Med (Maywood) |
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Autori principali: | , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
SAGE Publications
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471953/ https://ncbi.nlm.nih.gov/pubmed/25538133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214561590 |
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