Identification of a New Modulator of the Intercalated Disc in a Zebrafish Model of Arrhythmogenic Cardiomyopathy

Arrhythmogenic cardiomyopathy (ACM) is characterized by frequent cardiac arrhythmias. To elucidate the underlying mechanisms and discover potential chemical modifiers, we created a zebrafish model of ACM with cardiac myocyte–specific expression of the human 2057del2 mutation in the gene encoding pla...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Asimaki, Angeliki, Kapoor, Sudhir, Plovie, Eva, Arndt, Anne Karin, Adams, Edward, Liu, ZhenZhen, James, Cynthia A., Judge, Daniel P., Calkins, Hugh, Churko, Jared, Wu, Joseph C., MacRae, Calum A., Kléber, André G., Saffitz, Jeffrey E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471875/
https://ncbi.nlm.nih.gov/pubmed/24920660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008008
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