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Arrhythmogenic right ventricular cardiomyopathy mutations alter shear response without changes in cell–cell adhesion

AIMS: The majority of patients diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC) have mutations in genes encoding desmosomal proteins, raising the possibility that abnormal intercellular adhesion plays an important role in disease pathogenesis. We characterize cell mechanical pro...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Hariharan, Venkatesh, Asimaki, Angeliki, Michaelson, Jarett E., Plovie, Eva, MacRae, Calum A., Saffitz, Jeffrey E., Huang, Hayden
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296114/
https://ncbi.nlm.nih.gov/pubmed/25253076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu212
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