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Adaptor protein CRK induces epithelial–mesenchymal transition and metastasis of bladder cancer cells through HGF/c-Met feedback loop

We have previously reported that an adaptor protein CRK, including CRK-I and CRK-II, plays essential roles in the malignant potential of various aggressive human cancers, suggesting the validity of targeting CRK in molecular targeted therapy of a wide range of cancers. Nevertheless, the role of CRK...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Matsumoto, Ryuji, Tsuda, Masumi, Wang, Lei, Maishi, Nako, Abe, Takashige, Kimura, Taichi, Tanino, Mishie, Nishihara, Hiroshi, Hida, Kyoko, Ohba, Yusuke, Shinohara, Nobuo, Nonomura, Katsuya, Tanaka, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471787/
https://ncbi.nlm.nih.gov/pubmed/25816892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12662
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