Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer

The signaling adaptor protein Crk has been shown to play an important role in various human cancers. However, its regulatory machinery is not clear. Here, we demonstrated that Crk induced EMT in A549 human lung adenocarcinoma cells through differential regulation of Rac1/Snail and RhoA/Slug, leading...

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Udgivet i:Oncotarget
Main Authors: Elmansuri, Aiman Z., Tanino, Mishie A., Mahabir, Roshan, Wang, Lei, Kimura, Taichi, Nishihara, Hiroshi, Kinoshita, Ichiro, Dosaka-Akita, Hirotoshi, Tsuda, Masumi, Tanaka, Shinya
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053635/
https://ncbi.nlm.nih.gov/pubmed/27027347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8314
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