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Ligustrazine reduces blood-brain barrier permeability in a rat model of focal cerebral ischemia and reperfusion

Ligustrazine, also known as 2,3,5,6-tetramethylpyrazine (TMP), one of the major active compounds of Ligusticum wallichii Franchat., has been shown to reduce neuroinflammation and protect neurons during cerebral ischemia/reperfusion injury. However, whether it reduces blood-brain barrier (BBB) permea...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: TAN, FENG, FU, WENJUN, CHENG, NANFANG, MENG, DI, GU, YONG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471771/
https://ncbi.nlm.nih.gov/pubmed/26136889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2365
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