Mannan-modified adenovirus targeting TERT and VEGFR-2: A universal tumour vaccine

Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the comb...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Ying, Zhang, Jie, Wu, Yang, Ding, Zhen-Yu, Luo, Xin-Mei, Liu, Jie, Zhong, Wu-Ning, Deng, Guo-Hua, Xia, Xiang-Yu, Deng, Yao-Tiao, Wei, Yu-Quan, Jiang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471666/
https://ncbi.nlm.nih.gov/pubmed/26085010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11275
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