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Target-Based Whole-Cell Screening by (1)H NMR Spectroscopy**
An NMR-based approach marries the two traditional screening technologies (phenotypic and target-based screening) to find compounds inhibiting a specific enzymatic reaction in bacterial cells. Building on a previous study in which it was demonstrated that hydrolytic decomposition of meropenem in livi...
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| Gepubliceerd in: | Angew Chem Int Ed Engl |
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| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
WILEY-VCH Verlag
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471574/ https://ncbi.nlm.nih.gov/pubmed/25693499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201410701 |
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