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UvrD facilitates DNA repair by pulling RNA polymerase backwards
UvrD helicase is required for nucleotide excision repair, although its role in this process is not well defined. Here we show that Escherichia coli UvrD binds RNA polymerase during transcription elongation and, using its helicase/translocase activity, forces RNA polymerase to slide backward along DN...
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| Publié dans: | Nature |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471481/ https://ncbi.nlm.nih.gov/pubmed/24402227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12928 |
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