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A Short-term In Vivo Screen Using Fetal Testosterone Production, a Key Event in the Phthalate Adverse Outcome Pathway, to Predict Disruption of Sexual Differentiation

This study was designed to develop and validate a short-term in vivo protocol termed the Fetal Phthalate Screen (FPS) to detect phthalate esters (PEs) and other chemicals that disrupt fetal testosterone synthesis and testis gene expression in rats. We propose that the FPS can be used to screen chemi...

詳細記述

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書誌詳細
出版年:Toxicol Sci
主要な著者: Furr, Johnathan R., Lambright, Christy S., Wilson, Vickie S., Foster, Paul M., Gray, Leon E.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471440/
https://ncbi.nlm.nih.gov/pubmed/24798384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu081
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