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A Short-term In Vivo Screen Using Fetal Testosterone Production, a Key Event in the Phthalate Adverse Outcome Pathway, to Predict Disruption of Sexual Differentiation

This study was designed to develop and validate a short-term in vivo protocol termed the Fetal Phthalate Screen (FPS) to detect phthalate esters (PEs) and other chemicals that disrupt fetal testosterone synthesis and testis gene expression in rats. We propose that the FPS can be used to screen chemi...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Furr, Johnathan R., Lambright, Christy S., Wilson, Vickie S., Foster, Paul M., Gray, Leon E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471440/
https://ncbi.nlm.nih.gov/pubmed/24798384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu081
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