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Rapid evaluation of 25 key sphingolipids and phosphosphingolipids in human plasma by LC-MS/MS

We report on a new, sensitive, and fast LC-MS/MS method for the simultaneous determination of 25 key sphingolipid components in human plasma, including phosphorylated sphinganine and sphingosine, in a single 9-min run. This method enables an effective and high-throughput coverage of the metabolic ch...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Basit, Abdul, Piomelli, Daniele, Armirotti, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471391/
https://ncbi.nlm.nih.gov/pubmed/25749796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8585-6
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