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Permeation thresholds for hydrophilic small biomolecules across microvascular and epithelial barriers are predictable on basis of conserved biophysical properties

PURPOSE: Neutral small hydrophiles are permeable to varying degrees, across the aqueous pores of phospholipid bilayer protein channels, with their potential for permeation into cells being predictable, on the basis of hydrophilicity and size. Here, it is hypothesized that permeation thresholds for s...

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Detaylı Bibliyografya
Yayımlandı:In Silico Pharmacol
Yazar: Sarin, Hemant
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471070/
https://ncbi.nlm.nih.gov/pubmed/26820890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40203-015-0009-y
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