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Engineering an effective Mn-binding MRI reporter protein by subcellular targeting

PURPOSE: Manganese (Mn) is an effective contrast agent and biologically active metal, which has been widely utilized for Mn-enhanced MRI (MEMRI). The purpose of this study was to develop and test a Mn binding protein for use as an genetic reporter for MEMRI. METHODS: The bacterial Mn-binding protein...

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Veröffentlicht in:Magn Reson Med
Hauptverfasser: Bartelle, Benjamin B., Mana, Miyeko D., Suero-Abreu, Giselle A., Rodriguez, Joe J., Turnbull, Daniel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470876/
https://ncbi.nlm.nih.gov/pubmed/25522343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25566
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