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Signaling and subcellular targeting by membrane-binding domains.
Protein kinase C homology-1 and -2, FYVE, and pleckstrin homology domains are ubiquitous in eukaryotic signal transduction and membrane-trafficking proteins. These domains regulate subcellular localization and protein function by binding to lipid ligands embedded in cell membranes. Structural and bi...
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| Publié dans: | Annu Rev Biophys Biomol Struct |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Annual Reviews
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4781318/ https://ncbi.nlm.nih.gov/pubmed/10940243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biophys.29.1.49 |
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